Example of use of XplorMed
This step was relatively obvious and quick, since it implies only sorting your abstracts by the MeSH terms assigned to them in your input file. The resulting page (see Figure 4a) displays the groups for each major MeSH heading.
|Figure 4a. Abstracts sorted by MeSH category.|
|Figure 4. Abstracts sorted by MeSH category. MeSH category is indicated in the left column. The column in the middle indicates how many abstracts do you have for each class, and the rightmost column diplays the identifiers of the abtracts. Note that one abstract can belong to many classes. Note also that some abstracts may not been assigned (yet) to any MeSH category.|
The abstracts are linked to the MEDLINE database entries. For example, you could click at the '20354919' link and get to the corresponding PubMed entry (see Figure 4b):
|Figure 4b. Entry '20354919' in the MEDLINE database.|
|Figure 4b. Entry '12062547' in the MEDLINE database. Following the links from medline identifiers, you can examine the corresponding medline entry as displayed in PubMed.|
Now, you can take the next step by hitting the "Compute relationships between words" button. Notice that you can previously choose to do the next step only for the abstracts in some of the categories. For example, you may be interested only on the biochemical characterization of a protein family, and not in the genetic aspects of a disease. In such a case, you may select the "Chemical and Drugs" category and unselect the rest. In this example, we are just taking all the categories, although this is not advisable.